6Manometer and reaction vessels, “Warburg Apparatus“
around 1920s
Manometers are devices that can be used to measure the pressure of a gas.
In the 1920s, Otto Warburg and Erwin Negelein combined them with vessels in which biochemical reactions took place. They succeeded in determining aspects of the gas metabolism of tissues and cells – such as how much oxygen was consumed in a reaction, or how much carbon dioxide was produced. This manometric device is known as the Warburg apparatus.
You can find out more about the life and work of Erwin Negelein and Otto Warburg in the Science-historical tour.